The recent advances in nanotechnology, combined with modern tools from surface chemistry, have provided a considerable support to the exploration of biorecognition processes. In collaboration with the “Complex Fluids and Molecular Biophysics Lab” of the University of Milan, we have
Targeting molecules are produced by genetic engineering and purified in order to gain a high level of control on the number and orientation of the protein on the nanoparticle surface. We use a bimodular approach, in which the fusion protein
A primary challenge in cancer diagnosis is the development of effective molecular contrast agents for early detection of malignancies. Among the different kinds of tumors affecting human kind, mammary carcinoma is of particular importance, as it is the most common
TUMOR TARGETING. Drug-loaded nanoparticles can be used to target selective cancer cells resulting in the localization of the therapeutic action, which is expected to prevent the typical side-effects usually encountered with conventional chemotherapeutics. We are developing colloidal and biomimetic nanoparticles