Research interests: Her current scientific research is aimed to development of nanoparticles for biochemical and biomedical applications. It concerns the conception of new systems for drug delivery and targeting (colloidal and polymeric nanoparticles, nanoemulsions, prodrugs etc.). Her research interests focus on synthesis, characterization of colloidal nanoparticles and bio-functionalization using different approaches and different active bio-ligands for biomedical application mainly in the oncology field.
In order to support her research in new drug delivery nanosystems, in the past few years she has looked into new administration methods of nanoparticles rather than traditional intravenous ones, in particular oral and topic administrations.
https://www.scopus.com/authid/detail.uri?authorId=24922603100 (Scopus)
http://www.btbs.unimib.it/?personale-type=miriam-colombo&lang=en (Unimib)
Pubblicazioni Miriam Colombo
2019 - Recent advances in magnetic fluid hyperthermia for cancer therapy: Das, P., Colombo, M., & Prosperi, D. (2019). Recent advances in magnetic fluid hyperthermia for cancer therapy. COLLOIDS AND SURFACES. B, BIOINTERFACES, 174, 42-55.2019 - Pemetrexed-loaded nanoparticles targeted to malignant pleural mesothelioma cells: an in vitro study: Cova, E., Pandolfi, L., Colombo, M., Frangipane, V., Inghilleri, S., Morosini, M., et al. (2019). Pemetrexed-loaded nanoparticles targeted to malignant pleural mesothelioma cells: an in vitro study. INTERNATIONAL JOURNAL OF NANOMEDICINE, 14, 773-785.2019 - Suicide gene therapy: A new frontier for cancer fighting: Prosperi, D., & Colombo, M. (2019). Suicide gene therapy: A new frontier for cancer fighting. CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 20(1), 2-4.2019 - Multifunctional Magnetic Gold Nanomaterials for Cancer: Das, P., Fatehbasharzad, P., Colombo, M., Fiandra, L., & Prosperi, D. (2019). Multifunctional Magnetic Gold Nanomaterials for Cancer. TRENDS IN BIOTECHNOLOGY, 37(9), 995-1010.2019 - Imatinib-loaded gold nanoparticles inhibit proliferation of fibroblasts and macrophages from systemic sclerosis patients and ameliorate experimental bleomycin-induced lung fibrosis: Codullo, V., Cova, E., Pandolfi, L., Breda, S., Morosini, M., Frangipane, V., et al. (2019). Imatinib-loaded gold nanoparticles inhibit proliferation of fibroblasts and macrophages from systemic sclerosis patients and ameliorate experimental bleomycin-induced lung fibrosis. JOURNAL OF CONTROLLED RELEASE, 310, 198-208.2019 - Are nanotechnological approaches the future of treating inflammatory diseases?: Rizzuto, M., Salvioni, L., Rotem, R., Colombo, M., Zanoni, I., Granucci, F., et al. (2019). Are nanotechnological approaches the future of treating inflammatory diseases?. NANOMEDICINE, 14(17), 2379-2390.2019 - Monitoring the Fate of Orally Administered PLGA Nanoformulation for Local Delivery of Therapeutic Drugs: Morelli, L., Gimondi, S., Sevieri, M., Salvioni, L., Guizzetti, M., Colzani, B., et al. (2019). Monitoring the Fate of Orally Administered PLGA Nanoformulation for Local Delivery of Therapeutic Drugs. PHARMACEUTICS, 11(12).2019 - Thirty years of cancer nanomedicine: Success, frustration, and hope: Salvioni, L., Rizzuto, M., Bertolini, J., Pandolfi, L., Colombo, M., & Prosperi, D. (2019). Thirty years of cancer nanomedicine: Success, frustration, and hope. CANCERS, 11(12), 1855.2019 - Does conjugation strategy matter? Cetuximab-conjugated gold nanocages for targeting triple-negative breast cancer cells: Avvakumova, S., Pandolfi, L., Soprano, E., Moretto, L., Bellini, M., Galbiati, E., et al. (2019). Does conjugation strategy matter? Cetuximab-conjugated gold nanocages for targeting triple-negative breast cancer cells. NANOSCALE ADVANCES, 1(9), 3626-3638.2018 - Investigation of antitumor activities of trastuzumab delivered by PLGA nanoparticles: Colzani, B., Pandolfi, L., Hoti, A., Iovene, P., Natalello, A., Avvakumova, S., et al. (2018). Investigation of antitumor activities of trastuzumab delivered by PLGA nanoparticles. INTERNATIONAL JOURNAL OF NANOMEDICINE, 13, 957-973.Pubblicazioni unificate